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Postdoctoral researcher in Fungal Biology, Molecular Biology, and Biochemistry

National Center for Genetic Engineering and Biotechnology (BIOTEC)
  • National Center for Genetic Engineering and Biotechnology (BIOTEC)
  • Nonprofits / องค์กรไม่แสวงหาผลกำไร
  • 3179
  • 17 Nov 2016
  • 20 December 2016

Postdoctoral Researcher Position

at National Center for Genetic Engineering and Biotechnology (BIOTEC),

National Science and Technology Development Agency (NSTDA)

THAILAND

BIOTEC, part of the national center complex in Thailand, is seeking a postdoctoral researcher in Fungal Biology, Molecular Biology, and Biochemistry.  The successful candidate will be working on characterization of polyketide synthase (PKS) genes in the fungus Beauveria bassiana.  We have obtained the null mutant of which each of these PKS genes has been disrupted.   The main objective is to determine roles of these enzymes in pathogenesis against insects using the null mutants and the overexpressing mutants as tools.

Job description

Responsibilities include but not limited to

1)  Overexpression of these PKS genes in Beauveria bassiana. 2) Comparative study between wild type and the null- and overexpressing mutant strains in fungal physiology, biochemistry, and pathogenicity to insect hosts. 3) Cell wall analysis of the mutants compared to wild type by staining and component extraction. 4) Mass spectrometry analysis of fungal cells and cell walls and 5) Preparation of manuscripts for submission to peer-reviewed scientific journals.

Job Requirement

  • Ph.D. in Fungal Biology and Physiology, Genetics and Molecular Biology, Host-Microbe Interaction, Secondary Metabolite Biosynthesis, or Natural product Chemistry. • Basic knowledge of Mycology particularly with insect fungi. • Experienced in light, fluorescence/confocal, and electron microscopy.

Skills and Techniques

Extensive molecular techniques particularly with fungi (RT-PCR, real-time PCR, fungal transformation, etc.) are required.  Knowledge and skills in fungal histology, fungal pathogenicity test to insects, chemical analysis (HPLC, LC-MS, structural elucidation techniques), or green fluorescence protein (GFP) analysis are also needed.  Experience in working on the interaction between a pathogen and a host is an asset.

Application Submission (including CV, MS and/or PhD transcript, and publications) to Dr. Alongkorn Amnuaykanjanasin at alongkorn@biotec.or.th by Dec 20, 2016, or more details at

+66 2 5646700 ext. 3248, 3364.

 

Contact : alongkorn@biotec.or.th/ 02-5646700 ext 3248

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